Graduate Studies Faculty

Helene Bernstein, MD/PhD

Helene Bernstein, MD/PhD
Appointed 10/01/15
Women's Health Network
2105C Weiskotten Hall
766 Irving Ave.
Syracuse, NY 13210

315 464-8668

Current Appointments

Hospital Campus

  • Downtown

Clinical Section Affiliations

  • Obstetrics and Gynecology: Maternal and Fetal Medicine
  • Women's Health Network: Obstetric, Gynecology & Urogynecology

Research Programs and Affiliations

  • Biomedical Sciences Program
  • Obstetrics and Gynecology


Education & Fellowships

  • Fellowship: Johns Hopkins University School of Medicine, 2002, Maternal Fetal Medicine
  • Residency: Albany Medical College Hospital, 1999, Obstetrics and Gynecology
  • Internship: Washington University Barnes-Jewish Hospital, 1996, Obstetrics and Gynecology
  • MD: University of Alabama at Birmingham, 1995
  • PhD: University of Alabama at Birmingham, 1994, Microbiology and Immunology

Clinical Interests

  • Prenatal genetic diagnosis, medical complications, HIV and other viral infections during pregnancy

Education Interests

  • Interprofessional education and research

Research Interests

  • Immunoregulation of innate immune function influencing viral pathogenesis, pregnancy complications, and inflammation; understanding how magnesium regulates immune function

Clinical Trials

  • Magnesium Decreases Inflammatory Cytokine Production: A Novel, Important Innate Immunomodulatory Mechanism
    Read more

Specialties & Certification

  • Obstetrics and Gynecology
  • Maternal and Fetal Medicine

Diseases & Conditions Treated

  • Chickenpox During Pregnancy
  • Gestational Diabetes
  • HIV Infection and AIDS
  • Heart Conditions in Pregnancy
  • High Risk Pregnancies
  • Hypertension in Pregnancy
  • Toxoplasmosis During Pregnancy


  • Adults


  • Amniocentesis
  • Chorionic Villus Sampling (CVS) for Prenatal Diagnosis
  • Prenatal Ultrasound


  • American Institute of Ultrasound in Medicine (AIUM)
  • American Congress of Obstetricians and Gynecologists (ACOG)

Current Hospital Privileges

  • Upstate University Hospital
  • Crouse Hospital


Link to PubMed External Icon (Opens new window. Close the PubMed window to return to this page.)


My laboratory studies immunopathogenesis, focusing on understanding how innate immune function influences viral pathogenesis, pregnancy complications, and inflammation. Research themes include:

  • The influence of magnesium on inflammation
  • CD4 expression on NK cells
  • NK cell/ dendritic cell interactions
  • Immunologic determinants of perinatal HIV transmission
  • Immune function influences preterm parturition

Ongoing investigations elucidating immunopathogenic mechanisms of HIV infection and disease progression are complemented by related projects delineating the influence of maternal and neonatal immune activation and function on preterm parturition and investigating how magnesium regulates immune function.


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